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KMID : 0357919850190030374
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Korean Journal of Pathology
1985 Volume.19 No. 3 p.374 ~ p.376
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A Pathologic and Immunopathologic Study of Behcet's Syndrome
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Abstract
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The pathologic and immunopathologic findings of 15 skin biopsies of Behcet's
syndrome were studied to investigate the pathogenetic mechanism of this syndrome. The
age range was 28 to 50 years; male to female ratio was 1 : 1.2. Ulceration with acute
necrotizing and chronic nonspecific inflammation was present in most cases with
leukocytoclastic vasculitis and perivascular lymphohistiocytic, plasmocytic infiltrations.
Eight of 15cases showed C>3 deposit in the walls of venules and capillaries,
one of them was associated with IgM and fibrinogen deposits. With these findings
humoral factor seemed to play a main role in the pathogenesis of vasculitis observed in
Behcet's syndrome, but the possibility of other mechanisms operative in complex pattern
was also considered.
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KEYWORD
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